우리 연구실에서 "'Out-of-phase transcranial alternating current stimulation modulates the neurodynamics of inhibitory control"라는 제목으로, 진행한 연구가, 뇌영상분야 1위 국제 학술지인 NeuroImage에 게재되었습니다.
본 연구는 뇌의 활동 네트워크와 기본모드 네트워크 사이에 위상차 자극을 주어, 뇌의 주요 기능 중의 하나인 억제 기능을 효과적으로 제어하는 연구입니다.
Abstract:
Transcranial alternating current stimulation (tACS) is an efficient neuromodulation technique that enhances cognitive function in a non-invasive manner. Using functional magnetic resonance imaging, we investigated whether tACS with different phase lags (0 and 180 degrees) between the dorsal anterior cingulate and left dorsolateral prefrontal cortices modulated inhibitory control performance during the Stroop task. We found out-of-phase tACS mediated improvements in task performance, which was neurodynamically reflected as putamen, dorsolateral prefrontal, and primary motor cortical activation as well as prefrontal-based top-down functional connectivity. Our observations uncover the neurophysiological bases of tACS-phase-dependent neuromodulation and provide a feasible non-invasive approach to effectively modulate inhibitory control.
